A Small-Molecule Inhibitor of Human DNA Polymerase η Potentiates the Effects of Cisplatin in Tumor Cells | Biochemistry
DNA polymerases and cancer | Nature Reviews Cancer
DNA polymerase η promotes nonhomologous end joining upon etoposide exposure dependent on the scaffolding protein Kap1 - Journal of Biological Chemistry
Inhibition of Human DNA Polymerases Eta and Kappa by Indole-Derived Molecules Occurs through Distinct Mechanisms
DNA polymerase eta protects human cells against DNA damage induced by the tumor chemotherapeutic temozolomide - ScienceDirect
Frontiers | Inhibiting DNA Polymerases as a Therapeutic Intervention against Cancer
Inhibition of mutagenic translesion synthesis: A possible strategy for improving chemotherapy? | PLOS Genetics
DNA Polymerase Kappa Antibody (6F2) (H00051426-M01): Novus Biologicals
IJMS | Free Full-Text | Detours to Replication: Functions of Specialized DNA Polymerases during Oncogene-induced Replication Stress | HTML
Anti-DNA Polymerase Kappa/POLK antibody (ab86076) | Abcam
Regulation of the error-prone DNA polymerase Polκ by oncogenic signaling and its contribution to drug resistance | Science Signaling
DNA Polymerase Kappa Research Products: Novus Biologicals
RCSB PDB - 6BS1: Crystal Structure of Human DNA polymerase kappa in complex with DNA containing the major cisplatin lesion
Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery | eLife
Phosphorylation Alters the Properties of Pol η: Implications for Translesion Synthesis
Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery | eLife
Inhibition of Human DNA Polymerases Eta and Kappa by Indole-Derived Molecules Occurs through Distinct Mechanisms | ACS Chemical Biology
Molecules | Free Full-Text | Mammalian DNA Polymerase Kappa Activity and Specificity
Translesion synthesis DNA polymerase η exhibits a specific RNA extension activity and a transcription-associated function | Scientific Reports
Frontiers | Inhibiting DNA Polymerases as a Therapeutic Intervention against Cancer
Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery | eLife
Molecules | Free Full-Text | Mammalian DNA Polymerase Kappa Activity and Specificity | HTML
DNA polymerase eta: A potential pharmacological target for cancer therapy - Saha - 2021 - Journal of Cellular Physiology - Wiley Online Library
NF-κB inhibitors in treatment and prevention of lung cancer - ScienceDirect
Structural Basis for Human DNA Polymerase Kappa to Bypass Cisplatin Intrastrand Cross-Link (Pt-GG) Lesion as an Efficient and Accurate Extender - ScienceDirect
Translesion polymerase eta both facilitates DNA replication and promotes increased human genetic variation at common fragile sites | PNAS
